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Extracellular Vesicle Capture by AnTibody of CHoice and Enzymatic Release (EV‐CATCHER): A customizable purification assay designed for small‐RNA biomarker identification and evaluation of circulating small‐EVs

Circulating nucleic acids, encapsulated within small extracellular vesicles (EVs), provide a remote cellular snapshot of biomarkers derived from diseased tissues, however selective isolation is critical. Current laboratory‐based purification techniques rely on the physical properties of small‐EVs ra...

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Detalles Bibliográficos
Autores principales: Mitchell, Megan I., Ben‐Dov, Iddo Z., Liu, Christina, Ye, Kenny, Chow, Kar, Kramer, Yael, Gangadharan, Anju, Park, Steven, Fitzgerald, Sean, Ramnauth, Andrew, Perlin, David S., Donato, Michele, Bhoy, Emily, Manouchehri Doulabi, Ehsan, Poulos, Michael, Kamali‐Moghaddam, Masood, Loudig, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173589/
https://www.ncbi.nlm.nih.gov/pubmed/34122779
http://dx.doi.org/10.1002/jev2.12110