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Age influences susceptibility of brain capillary endothelial cells to La Crosse virus infection and cell death

BACKGROUND: A key factor in the development of viral encephalitis is a virus crossing the blood-brain barrier (BBB). We have previously shown that age-related susceptibility of mice to the La Crosse virus (LACV), the leading cause of pediatric arbovirus encephalitis in the USA, was associated with t...

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Detalles Bibliográficos
Autores principales: Basu, Rahul, Nair, Vinod, Winkler, Clayton W., Woods, Tyson A., Fraser, Iain D. C., Peterson, Karin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173794/
https://www.ncbi.nlm.nih.gov/pubmed/34082753
http://dx.doi.org/10.1186/s12974-021-02173-4