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Upregulated microRNA let-7a accelerates apoptosis and inhibits proliferation in uterine junctional zone smooth muscle cells in adenomyosis under conditions of a normal activated hippo-YAP1 axis

BACKGROUND: Let-7a is a small non-coding RNA that has been found to take part in cell proliferation and apoptosis. The hippo-YAP1 axis, known as a tumour suppressor pathway, also plays an important role in cell proliferation and apoptosis. YAP1, TAZ, and phospho-YAP1 play key roles in actions of the...

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Detalles Bibliográficos
Autores principales: Huang, Jun-Hua, Duan, Hua, Wang, Sha, Wang, Yi-Yi, LV, Cheng-Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173847/
https://www.ncbi.nlm.nih.gov/pubmed/34082774
http://dx.doi.org/10.1186/s12958-021-00753-w