Genome sequences of human cytomegalovirus strain TB40/E variants propagated in fibroblasts and epithelial cells

The advent of whole genome sequencing has revealed that common laboratory strains of human cytomegalovirus (HCMV) have major genetic deficiencies resulting from serial passage in fibroblasts. In particular, tropism for epithelial and endothelial cells is lost due to mutations disrupting genes UL128,...

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Detalles Bibliográficos
Autores principales: Al Qaffas, Ahmed, Camiolo, Salvatore, Vo, Mai, Aguiar, Alexis, Ourahmane, Amine, Sorono, Myrna, Davison, Andrew J., McVoy, Michael A., Hertel, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173854/
https://www.ncbi.nlm.nih.gov/pubmed/34082757
http://dx.doi.org/10.1186/s12985-021-01583-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173854/
https://www.ncbi.nlm.nih.gov/pubmed/34082757
http://dx.doi.org/10.1186/s12985-021-01583-3

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