Cargando…

Exosomal circ-BRWD1 contributes to osteoarthritis development through the modulation of miR-1277/TRAF6 axis

BACKGROUND: Circular RNAs (circRNAs) can act as vital players in osteoarthritis (OA). However, the roles of circRNAs in OA remain obscure. Herein, we explored the roles of exosomal circRNA bromodomain and WD repeat domain containing 1(circ-BRWD1) in OA pathology. METHODS: In vitro model of OA was co...

Descripción completa

Detalles Bibliográficos
Autores principales: Guo, Zhenye, Wang, Huan, Zhao, Feng, Liu, Min, Wang, Feida, Kang, Mingming, He, Weifu, Lv, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173917/
https://www.ncbi.nlm.nih.gov/pubmed/34082824
http://dx.doi.org/10.1186/s13075-021-02541-8