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Human amnion-derived mesenchymal stem cells improved the reproductive function of age-related diminished ovarian reserve in mice through Ampk/FoxO3a signaling pathway

BACKGROUND: Age-related diminished ovarian reserve (AR-DOR) reduced the quality of oocytes, resulting in decreased female fertility. Aging is tightly related to abnormal distribution and function of mitochondria, while mitophagy is a major process to maintain normal quality and quantity of mitochond...

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Detalles Bibliográficos
Autores principales: Liu, Hanwen, Jiang, Chunyan, La, Boya, Cao, Meng, Ning, Song, Zhou, Jing, Yan, Zhengjie, Li, Chuyu, Cui, Yugui, Ma, Xiang, Wang, Meilian, Chen, Li, Yu, Youjia, Chen, Feng, Zhang, Yuexin, Wu, Huimin, Liu, Jiayin, Qin, Lianju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173966/
https://www.ncbi.nlm.nih.gov/pubmed/34078462
http://dx.doi.org/10.1186/s13287-021-02382-x