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Investigation of the Optimal Dose aPCC in Reversing the Effect of Factor Xa Inhibitors—An In Vitro Study

Factor (F) Xa inhibitors are safe and effective alternatives to warfarin. There are concerns about the lack of a reversal strategy in case of serious bleeds or need for emergency surgery in situations when the antidote andexanet alfa is not available. Factor concentrates are widely used, but there a...

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Detalles Bibliográficos
Autores principales: Schultz, Nina Haagenrud, Fareed, Jawed, Holme, Pål Andre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173996/
https://www.ncbi.nlm.nih.gov/pubmed/34060371
http://dx.doi.org/10.1177/10760296211021156