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Aberrant Axo-Axonic Synaptic Reorganization in the Phosphorylated L1-CAM/Calcium Channel Subunit α2δ−1-Containing Central Terminals of Injured c-Fibers in the Spinal Cord of a Neuropathic Pain Model

In the dorsal horn of the spinal cord, peripheral nerve injury induces structural and neurochemical alterations through which aberrant synaptic signals contribute to the formation of neuropathic pain. However, the role of injured primary afferent terminals in such plastic changes remain unclear. In...

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Detalles Bibliográficos
Autores principales: Yamanaka, Hiroki, Okubo, Masamichi, Kobayashi, Kimiko, Noguchi, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8174056/
https://www.ncbi.nlm.nih.gov/pubmed/33500315
http://dx.doi.org/10.1523/ENEURO.0499-20.2021