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Cardiac‐Specific Deletion of Orai3 Leads to Severe Dilated Cardiomyopathy and Heart Failure in Mice
BACKGROUND: Orai3 is a mammalian‐specific member of the Orai family (Orai1‒3) and a component of the store‐operated Ca(2+) entry channels. There is little understanding of the role of Orai channels in cardiomyocytes, and its role in cardiac function remains unexplored. Thus, we developed mice lackin...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8174158/ https://www.ncbi.nlm.nih.gov/pubmed/33849280 http://dx.doi.org/10.1161/JAHA.120.019486 |