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Genetically Proxied Inhibition of Coagulation Factors and Risk of Cardiovascular Disease: A Mendelian Randomization Study

BACKGROUND: We conducted Mendelian randomization analyses investigating the linear associations of genetically proxied inhibition of different coagulation factors with risk of common cardiovascular diseases. METHODS AND RESULTS: Genetic instruments proxying coagulation factor inhibition were identif...

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Detalles Bibliográficos
Autores principales: Yuan, Shuai, Burgess, Stephen, Laffan, Mike, Mason, Amy M., Dichgans, Martin, Gill, Dipender, Larsson, Susanna C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8174173/
https://www.ncbi.nlm.nih.gov/pubmed/33834859
http://dx.doi.org/10.1161/JAHA.120.019644