Direct Cardiac Actions of the Sodium Glucose Co‐Transporter 2 Inhibitor Empagliflozin Improve Myocardial Oxidative Phosphorylation and Attenuate Pressure‐Overload Heart Failure

BACKGROUND: We determined if the sodium glucose co‐transporter 2 inhibitor empagliflozin attenuates pressure overload‐induced heart failure in non‐diabetic mellitus mice by direct cardiac effects and the mechanisms involved. METHODS AND RESULTS: Male C57BL/6J mice (4–6 months of age) were subjected...

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Detalles Bibliográficos
Autores principales: Li, Xuan, Lu, Qingguo, Qiu, Yunguang, do Carmo, Jussara M., Wang, Zhen, da Silva, Alexandre A., Mouton, Alan, Omoto, Ana C. M., Hall, Michael E., Li, Ji, Hall, John E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8174202/
https://www.ncbi.nlm.nih.gov/pubmed/33719499
http://dx.doi.org/10.1161/JAHA.120.018298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8174202/
https://www.ncbi.nlm.nih.gov/pubmed/33719499
http://dx.doi.org/10.1161/JAHA.120.018298

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