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Cardiotoxic Effect of Modern Anthracycline Dosing on Left Ventricular Ejection Fraction: A Systematic Review and Meta‐Analysis of Placebo Arms From Randomized Controlled Trials

BACKGROUND: Anthracyclines are a key chemotherapeutic agent used against hematological and solid organ malignancies. However, their benefits in cancer survival are limited by cumulative, dose‐related cardiotoxicity. The impact of anthracyclines on left ventricular ejection fraction (LVEF), in the er...

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Detalles Bibliográficos
Autores principales: Jeyaprakash, Prajith, Sangha, Sukhmandeep, Ellenberger, Katherine, Sivapathan, Shanthosh, Pathan, Faraz, Negishi, Kazuaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8174208/
https://www.ncbi.nlm.nih.gov/pubmed/33660514
http://dx.doi.org/10.1161/JAHA.120.018802