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Biological Pathways in Adolescent Aortic Stiffness

BACKGROUND: Aortic stiffening begins in youth and antedates future hypertension. In adults, excess weight, systemic inflammation, dyslipidemia, insulin resistance, neurohormonal activation, and altered adipokines are implicated in the pathogenesis of increased aortic stiffness. In adolescents, we as...

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Detalles Bibliográficos
Autores principales: Zachariah, Justin P., Wang, Yunfei, Newburger, Jane W., deFerranti, Sarah D., Mitchell, Gary F, Vasan, Ramachandran S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8174212/
https://www.ncbi.nlm.nih.gov/pubmed/33641350
http://dx.doi.org/10.1161/JAHA.120.018419