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Sirtuin 3 Alleviates Diabetic Cardiomyopathy by Regulating TIGAR and Cardiomyocyte Metabolism

BACKGROUND: Impairment of glycolytic metabolism is suggested to contribute to diabetic cardiomyopathy. In this study, we explored the roles of SIRT3 (Sirtuin 3) on cardiomyocyte glucose metabolism and cardiac function. METHODS AND RESULTS: Exposure of H9c2 cardiomyocyte cell lines to high glucose (H...

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Detalles Bibliográficos
Autores principales: Li, Lanfang, Zeng, Heng, He, Xiaochen, Chen, Jian‐Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8174281/
https://www.ncbi.nlm.nih.gov/pubmed/33586458
http://dx.doi.org/10.1161/JAHA.120.018913