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Deficiency of ITGAM Attenuates Experimental Abdominal Aortic Aneurysm in Mice

BACKGROUND: Integrin αM (CD11b), which is encoded by the Integrin Subunit Alpha M (ITGAM) gene, is not only a surface marker of monocytes but also an essential adhesion molecule. In this study, we investigated the effect of CD11b on experimental abdominal aortic aneurysm and the potential underlying...

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Detalles Bibliográficos
Autores principales: Zhou, Min, Wang, Xia, Shi, Yiqin, Ding, Yong, Li, Xu, Xie, Tianchen, Shi, Zhenyu, Fu, Weiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8174368/
https://www.ncbi.nlm.nih.gov/pubmed/33749307
http://dx.doi.org/10.1161/JAHA.120.019900