Testosterone Metabolite 6β‐Hydroxytestosterone Contributes to Angiotensin II‐Induced Abdominal Aortic Aneurysms in Apoe (–/–) Male Mice

BACKGROUND: Sex is a prominent risk factor for abdominal aortic aneurysms (AAAs), and angiotensin II (Ang II) induces AAA formation to a greater degree in male than in female mice. We previously reported that cytochrome P450 1B1 contributes to the development of hypertension, as well as AAAs, in mal...

Descripción completa

Detalles Bibliográficos
Autores principales: Mukherjee, Kamalika, Pingili, Ajeeth K., Singh, Purnima, Dhodi, Ahmad N., Dutta, Shubha R., Gonzalez, Frank J., Malik, Kafait U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8174379/
https://www.ncbi.nlm.nih.gov/pubmed/33719500
http://dx.doi.org/10.1161/JAHA.120.018536

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8174379/
https://www.ncbi.nlm.nih.gov/pubmed/33719500
http://dx.doi.org/10.1161/JAHA.120.018536

Ejemplares similares