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Testosterone Metabolite 6β‐Hydroxytestosterone Contributes to Angiotensin II‐Induced Abdominal Aortic Aneurysms in Apoe (–/–) Male Mice

BACKGROUND: Sex is a prominent risk factor for abdominal aortic aneurysms (AAAs), and angiotensin II (Ang II) induces AAA formation to a greater degree in male than in female mice. We previously reported that cytochrome P450 1B1 contributes to the development of hypertension, as well as AAAs, in mal...

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Detalles Bibliográficos
Autores principales:	Mukherjee, Kamalika, Pingili, Ajeeth K., Singh, Purnima, Dhodi, Ahmad N., Dutta, Shubha R., Gonzalez, Frank J., Malik, Kafait U.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8174379/ https://www.ncbi.nlm.nih.gov/pubmed/33719500 http://dx.doi.org/10.1161/JAHA.120.018536

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