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Ketamine-induced neurotoxicity in neurodevelopment: A synopsis of main pathways based on recent in vivo experimental findings

Ketamine, a phencyclidine derivative and N-methyl-D-aspartate (NMDA) receptor antagonist, is widely used as an anesthetic, analgesic, and sedative agent in daily pediatric practice. Experimental studies have suggested that early prenatal or postnatal exposure to ketamine can induce neuroapoptosis, a...

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Detalles Bibliográficos
Autores principales: Kalopita, Konstantina, Armakolas, Athanasios, Philippou, Anastassios, Zarros, Apostolos, Angelogianni, Panagoula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8174420/
https://www.ncbi.nlm.nih.gov/pubmed/34103820
http://dx.doi.org/10.4103/joacp.JOACP_415_19