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Ketamine-induced neurotoxicity in neurodevelopment: A synopsis of main pathways based on recent in vivo experimental findings
Ketamine, a phencyclidine derivative and N-methyl-D-aspartate (NMDA) receptor antagonist, is widely used as an anesthetic, analgesic, and sedative agent in daily pediatric practice. Experimental studies have suggested that early prenatal or postnatal exposure to ketamine can induce neuroapoptosis, a...
Autores principales: | Kalopita, Konstantina, Armakolas, Athanasios, Philippou, Anastassios, Zarros, Apostolos, Angelogianni, Panagoula |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8174420/ https://www.ncbi.nlm.nih.gov/pubmed/34103820 http://dx.doi.org/10.4103/joacp.JOACP_415_19 |
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