Structure-based virtual screening of highly potent inhibitors of the nematode chitinase CeCht1

Nematode chitinases play vital roles in various physiological processes, including egg hatching, larva moulting, and reproduction. Small-molecule inhibitors of nematode chitinases have potential applications for controlling nematode pests. On the basis of the crystal structure of CeCht1, a represent...

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Detalles Bibliográficos
Autores principales: Chen, Wei, Chen, Qi, Kumar, Ashutosh, Jiang, Xi, Zhang, Kam Y. J., Yang, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8174485/
https://www.ncbi.nlm.nih.gov/pubmed/34074203
http://dx.doi.org/10.1080/14756366.2021.1931862

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8174485/
https://www.ncbi.nlm.nih.gov/pubmed/34074203
http://dx.doi.org/10.1080/14756366.2021.1931862

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