Synthesis and preliminary structure-activity relationship study of 3-methylquinazolinone derivatives as EGFR inhibitors with enhanced antiproliferative activities against tumour cells

In this paper, a set of 3-methylquniazolinone derivatives were designed, synthesised, and studied the preliminary structure-activity relationship for antiproliferative activities. All target compounds performed significantly inhibitory effects against wild type epidermal growth factor receptor tyros...

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Detalles Bibliográficos
Autores principales: Zhang, Yan, Wang, Qin, Li, Luolan, Le, Yi, Liu, Li, Yang, Jing, Li, Yongliang, Bao, Guochen, Yan, Longjia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8174486/
https://www.ncbi.nlm.nih.gov/pubmed/34074193
http://dx.doi.org/10.1080/14756366.2021.1933466

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8174486/
https://www.ncbi.nlm.nih.gov/pubmed/34074193
http://dx.doi.org/10.1080/14756366.2021.1933466

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