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4-Arylthiosemicarbazide derivatives as a new class of tyrosinase inhibitors and anti-Toxoplasma gondii agents

We report herein anti-proliferation effects of 4-arylthiosemicarbazides, with a cyclopentane substitution at N1 position, on highly virulent RH strain of Toxoplasma gondii. Among them, the highest in vitro anti-Toxoplasma activity was found with the meta-iodo derivative. Further experiments demonstr...

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Detalles Bibliográficos
Autores principales: Bekier, Adrian, Węglińska, Lidia, Paneth, Agata, Paneth, Piotr, Dzitko, Katarzyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8174488/
https://www.ncbi.nlm.nih.gov/pubmed/34074198
http://dx.doi.org/10.1080/14756366.2021.1931164