Leveraging eQTLs to identify individual-level tissue of interest for a complex trait

Genetic predisposition for complex traits often acts through multiple tissues at different time points during development. As a simple example, the genetic predisposition for obesity could be manifested either through inherited variants that control metabolism through regulation of genes expressed i...

Descripción completa

Detalles Bibliográficos
Autores principales: Majumdar, Arunabha, Giambartolomei, Claudia, Cai, Na, Haldar, Tanushree, Schwarz, Tommer, Gandal, Michael, Flint, Jonathan, Pasaniuc, Bogdan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8174686/
https://www.ncbi.nlm.nih.gov/pubmed/34019542
http://dx.doi.org/10.1371/journal.pcbi.1008915

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8174686/
https://www.ncbi.nlm.nih.gov/pubmed/34019542
http://dx.doi.org/10.1371/journal.pcbi.1008915

Ejemplares similares