Cargando…
Leveraging eQTLs to identify individual-level tissue of interest for a complex trait
Genetic predisposition for complex traits often acts through multiple tissues at different time points during development. As a simple example, the genetic predisposition for obesity could be manifested either through inherited variants that control metabolism through regulation of genes expressed i...
Autores principales: | Majumdar, Arunabha, Giambartolomei, Claudia, Cai, Na, Haldar, Tanushree, Schwarz, Tommer, Gandal, Michael, Flint, Jonathan, Pasaniuc, Bogdan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8174686/ https://www.ncbi.nlm.nih.gov/pubmed/34019542 http://dx.doi.org/10.1371/journal.pcbi.1008915 |
Ejemplares similares
-
Optimized design of single-cell RNA sequencing experiments for cell-type-specific eQTL analysis
por: Mandric, Igor, et al.
Publicado: (2020) -
Leveraging supervised learning for functionally informed fine-mapping of cis-eQTLs identifies an additional 20,913 putative causal eQTLs
por: Wang, Qingbo S., et al.
Publicado: (2021) -
Mapping QTLs for oil traits and eQTLs for oleosin genes in jatropha
por: Liu, Peng, et al.
Publicado: (2011) -
Genome-wide eQTLs and heritability for gene expression traits in unrelated individuals
por: Yang, Shengjie, et al.
Publicado: (2014) -
Leveraging input and output structures for joint mapping of epistatic and marginal eQTLs
por: Lee, Seunghak, et al.
Publicado: (2012)