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Histone tails cooperate to control the breathing of genomic nucleosomes

Genomic DNA is packaged in chromatin, a dynamic fiber variable in size and compaction. In chromatin, repeating nucleosome units wrap 145–147 DNA basepairs around histone proteins. Genetic and epigenetic regulation of genes relies on structural transitions in chromatin which are driven by intra- and...

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Detalles Bibliográficos
Autores principales: Huertas, Jan, Schöler, Hans Robert, Cojocaru, Vlad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8174689/
https://www.ncbi.nlm.nih.gov/pubmed/34081696
http://dx.doi.org/10.1371/journal.pcbi.1009013