Deep amplicon sequencing for culture-free prediction of susceptibility or resistance to 13 anti-tuberculous drugs

Conventional molecular tests for detecting Mycobacterium tuberculosis complex (MTBC) drug resistance on clinical samples cover a limited set of mutations. Whole-genome sequencing (WGS) typically requires culture. Here, we evaluated the Deeplex Myc-TB targeted deep-sequencing assay for prediction of...

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Detalles Bibliográficos
Autores principales: Jouet, Agathe, Gaudin, Cyril, Badalato, Nelly, Allix-Béguec, Caroline, Duthoy, Stéphanie, Ferré, Alice, Diels, Maren, Laurent, Yannick, Contreras, Sandy, Feuerriegel, Silke, Niemann, Stefan, André, Emmanuel, Kaswa, Michel K., Tagliani, Elisa, Cabibbe, Andrea, Mathys, Vanessa, Cirillo, Daniela, de Jong, Bouke C., Rigouts, Leen, Supply, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8174722/
https://www.ncbi.nlm.nih.gov/pubmed/32943401
http://dx.doi.org/10.1183/13993003.02338-2020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8174722/
https://www.ncbi.nlm.nih.gov/pubmed/32943401
http://dx.doi.org/10.1183/13993003.02338-2020

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