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Role of KLHL3 and dietary K(+) in regulating KS-WNK1 expression

The physiological role of the shorter isoform of with no lysine kinase (WNK)1 that is exclusively expressed in the kidney (KS-WNK1), with particular abundance in the distal convoluted tubule, remains elusive. KS-WNK1, despite lacking the kinase domain, is nevertheless capable of stimulating the NaCl...

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Detalles Bibliográficos
Autores principales: Ostrosky-Frid, Mauricio, Chávez-Canales, María, Zhang, Jinwei, Andrukhova, Olena, Argaiz, Eduardo R., Lerdo-de-Tejada, Fernando, Murillo-de-Ozores, Adrian, Sanchez-Navarro, Andrea, Rojas-Vega, Lorena, Bobadilla, Norma A., Vazquez, Norma, Castañeda-Bueno, María, Alessi, Dario R., Gamba, Gerardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8174809/
https://www.ncbi.nlm.nih.gov/pubmed/33682442
http://dx.doi.org/10.1152/ajprenal.00575.2020