HSPCs display within-family homogeneity in differentiation and proliferation despite population heterogeneity

High-throughput single-cell methods have uncovered substantial heterogeneity in the pool of hematopoietic stem and progenitor cells (HSPCs), but how much instruction is inherited by offspring from their heterogeneous ancestors remains unanswered. Using a method that enables simultaneous determinatio...

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Detalles Bibliográficos
Autores principales: Tak, Tamar, Prevedello, Giulio, Simon, Gaël, Paillon, Noémie, Benlabiod, Camélia, Marty, Caroline, Plo, Isabelle, Duffy, Ken R, Perié, Leïla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Stem Cells and Regenerative Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175087/
https://www.ncbi.nlm.nih.gov/pubmed/34002698
http://dx.doi.org/10.7554/eLife.60624

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175087/
https://www.ncbi.nlm.nih.gov/pubmed/34002698
http://dx.doi.org/10.7554/eLife.60624

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