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HSPCs display within-family homogeneity in differentiation and proliferation despite population heterogeneity
High-throughput single-cell methods have uncovered substantial heterogeneity in the pool of hematopoietic stem and progenitor cells (HSPCs), but how much instruction is inherited by offspring from their heterogeneous ancestors remains unanswered. Using a method that enables simultaneous determinatio...
Autores principales: | Tak, Tamar, Prevedello, Giulio, Simon, Gaël, Paillon, Noémie, Benlabiod, Camélia, Marty, Caroline, Plo, Isabelle, Duffy, Ken R, Perié, Leïla |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175087/ https://www.ncbi.nlm.nih.gov/pubmed/34002698 http://dx.doi.org/10.7554/eLife.60624 |
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