Mangifera indica Extracts as Novel PKM2 Inhibitors for Treatment of Triple Negative Breast Cancer

Pyruvate kinase (PK), a key enzyme that determines glycolytic activity, has been known to support the metabolic phenotype of tumor cells, and specific pyruvate kinase isoform M2 (PKM2) has been reported to fulfill divergent biosynthetic and energetic requirements of cancerous cells. PKM2 is overexpr...

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Detalles Bibliográficos
Autores principales: Rasul, Azhar, Riaz, Ammara, Wei, Wei, Sarfraz, Iqra, Hassan, Mudassir, Li, Jiang, Asif, Faryal, Adem, Şevki, Bukhari, Shazia Anwer, Asrar, Muhammad, Li, Xiaomeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175167/
https://www.ncbi.nlm.nih.gov/pubmed/34136566
http://dx.doi.org/10.1155/2021/5514669

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175167/
https://www.ncbi.nlm.nih.gov/pubmed/34136566
http://dx.doi.org/10.1155/2021/5514669

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