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Recent Advances in Single-Cell Profiling and Multispecific Therapeutics: Paving the Way for a New Era of Precision Medicine Targeting Cardiac Fibroblasts

PURPOSE OF REVIEW: Cardiac fibroblast activation contributes to fibrosis, maladaptive remodeling and heart failure progression. This review summarizes the latest findings on cardiac fibroblast activation dynamics derived from single-cell transcriptomic analyses and discusses how this information may...

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Detalles Bibliográficos
Autores principales: Shi, Sally Yu, Luo, Xin, Yamawaki, Tracy M., Li, Chi-Ming, Ason, Brandon, Furtado, Milena B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175296/
https://www.ncbi.nlm.nih.gov/pubmed/34081224
http://dx.doi.org/10.1007/s11886-021-01517-z