Differential associations of APOE-ε2 and APOE-ε4 alleles with PET-measured amyloid-β and tau deposition in older individuals without dementia

PURPOSE: To examine associations between the APOE-ε2 and APOE-ε4 alleles and core Alzheimer’s disease (AD) pathological hallmarks as measured by amyloid-β (Aβ) and tau PET in older individuals without dementia. METHODS: We analyzed data from 462 ADNI participants without dementia who underwent Aβ ([...

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Detalles Bibliográficos
Autores principales: Salvadó, Gemma, Grothe, Michel J., Groot, Colin, Moscoso, Alexis, Schöll, Michael, Gispert, Juan Domingo, Ossenkoppele, Rik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175302/
https://www.ncbi.nlm.nih.gov/pubmed/33521872
http://dx.doi.org/10.1007/s00259-021-05192-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175302/
https://www.ncbi.nlm.nih.gov/pubmed/33521872
http://dx.doi.org/10.1007/s00259-021-05192-8

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