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Purification of antibody fragments via interaction with detergent micellar aggregates

The research described in this report seeks to present proof-of-concept for a novel and robust platform for purification of antibody fragments and to define and optimize the controlling parameters. Purification of antigen-binding F(ab′)(2) fragments is achieved in the absence of chromatographic medi...

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Detalles Bibliográficos
Autores principales: Dhandapani, Gunasekaran, Wachtel, Ellen, Das, Ishita, Sheves, Mordechai, Patchornik, Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175343/
https://www.ncbi.nlm.nih.gov/pubmed/34083598
http://dx.doi.org/10.1038/s41598-021-90966-1