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Drug repurposing screens identify chemical entities for the development of COVID-19 interventions

The ongoing pandemic caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), necessitates strategies to identify prophylactic and therapeutic drug candidates for rapid clinical deployment. Here, we describe a screening pipeline for the discovery of efficacious SARS-CoV-2 in...

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Detalles Bibliográficos
Autores principales: Bakowski, Malina A., Beutler, Nathan, Wolff, Karen C., Kirkpatrick, Melanie G., Chen, Emily, Nguyen, Tu-Trinh H., Riva, Laura, Shaabani, Namir, Parren, Mara, Ricketts, James, Gupta, Anil K., Pan, Kastin, Kuo, Peiting, Fuller, MacKenzie, Garcia, Elijah, Teijaro, John R., Yang, Linlin, Sahoo, Debashis, Chi, Victor, Huang, Edward, Vargas, Natalia, Roberts, Amanda J., Das, Soumita, Ghosh, Pradipta, Woods, Ashley K., Joseph, Sean B., Hull, Mitchell V., Schultz, Peter G., Burton, Dennis R., Chatterjee, Arnab K., McNamara, Case W., Rogers, Thomas F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175350/
https://www.ncbi.nlm.nih.gov/pubmed/34083527
http://dx.doi.org/10.1038/s41467-021-23328-0