IRE1α RIDD activity induced under ER stress drives neuronal death by the degradation of 14-3-3 θ mRNA in cortical neurons during glucose deprivation

Altered protein homeostasis is associated with neurodegenerative diseases and acute brain injury induced under energy depletion conditions such as ischemia. The accumulation of damaged or unfolded proteins triggers the unfolded protein response (UPR), which can act as a homeostatic response or lead...

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Detalles Bibliográficos
Autores principales: Gómora-García, Juan Carlos, Gerónimo-Olvera, Cristian, Pérez-Martínez, Xochitl, Massieu, Lourdes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175356/
https://www.ncbi.nlm.nih.gov/pubmed/34083523
http://dx.doi.org/10.1038/s41420-021-00518-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175356/
https://www.ncbi.nlm.nih.gov/pubmed/34083523
http://dx.doi.org/10.1038/s41420-021-00518-9

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