Structural basis of complex formation between mitochondrial anion channel VDAC1 and Hexokinase-II

Complex formation between hexokinase-II (HKII) and the mitochondrial VDAC1 is crucial to cell growth and survival. We hypothesize that HKII first inserts into the outer membrane of mitochondria (OMM) and then interacts with VDAC1 on the cytosolic leaflet of OMM to form a binary complex. To systemati...

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Detalles Bibliográficos
Autores principales: Haloi, Nandan, Wen, Po-Chao, Cheng, Qunli, Yang, Meiying, Natarajan, Gayathri, Camara, Amadou K. S., Kwok, Wai-Meng, Tajkhorshid, Emad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175357/
https://www.ncbi.nlm.nih.gov/pubmed/34083717
http://dx.doi.org/10.1038/s42003-021-02205-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175357/
https://www.ncbi.nlm.nih.gov/pubmed/34083717
http://dx.doi.org/10.1038/s42003-021-02205-y

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