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Hemodialysis exacerbates proteolytic imbalance and pro-fibrotic platelet dysfunction

Multi-organ fibrosis among end stage renal disease (ESRD) patients cannot be explained by uremia alone. Despite mitigation of thrombosis during hemodialysis (HD), subsequent platelet dysfunction and tissue dysregulation are less understood. We comprehensively profiled plasma and platelets from ESRD...

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Detalles Bibliográficos
Autores principales: Velasquez-Mao, Aaron J., Velasquez, Mark A., Hui, Zhengxiong, Armas-Ayon, Denise, Wang, Jingshen, Vandsburger, Moriel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175411/
https://www.ncbi.nlm.nih.gov/pubmed/34083719
http://dx.doi.org/10.1038/s41598-021-91416-8