The chaperonin CCT8 controls proteostasis essential for T cell maturation, selection, and function

T cells rely for their development and function on the correct folding and turnover of proteins generated in response to a broad range of molecular cues. In the absence of the eukaryotic type II chaperonin complex, CCT, T cell activation induced changes in the proteome are compromised including the...

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Detalles Bibliográficos
Autores principales: Oftedal, Bergithe E., Maio, Stefano, Handel, Adam E., White, Madeleine P. J., Howie, Duncan, Davis, Simon, Prevot, Nicolas, Rota, Ioanna A., Deadman, Mary E., Kessler, Benedikt M., Fischer, Roman, Trede, Nikolaus S., Sezgin, Erdinc, Maizels, Rick M., Holländer, Georg A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175432/
https://www.ncbi.nlm.nih.gov/pubmed/34083746
http://dx.doi.org/10.1038/s42003-021-02203-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175432/
https://www.ncbi.nlm.nih.gov/pubmed/34083746
http://dx.doi.org/10.1038/s42003-021-02203-0

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