Validation of mathematical model with phosphate activation effect by batch (R)-phenylacetylcarbinol biotransformation process utilizing Candida tropicalis pyruvate decarboxylase in phosphate buffer

The (R)-phenylacetylcarbinol (PAC) batch biotransformation kinetics for partially purified Candida tropicalis TISTR 5350 pyruvate decarboxylase (PDC) were determined to validate a comprehensive mathematical model in 250 mL scale with 250 mM phosphate buffer/pH 7.0. PDC could convert initial 100/120 ...

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Detalles Bibliográficos
Autores principales: Khemacheewakul, Julaluk, Taesuwan, Siraphat, Nunta, Rojarej, Techapun, Charin, Phimolsiripol, Yuthana, Rachtanapun, Pornchai, Jantanasakulwong, Kittisak, Porninta, Kritsadaporn, Sommanee, Sumeth, Mahakuntha, Chatchadaporn, Chaiyaso, Thanongsak, Seesuriyachan, Phisit, Reungsang, Alissara, Trinh, Ngoc Thao Ngan, Wangtueai, Sutee, Sommano, Sarana Rose, Leksawasdi, Noppol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175490/
https://www.ncbi.nlm.nih.gov/pubmed/34083711
http://dx.doi.org/10.1038/s41598-021-91294-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175490/
https://www.ncbi.nlm.nih.gov/pubmed/34083711
http://dx.doi.org/10.1038/s41598-021-91294-0

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