Synergistic sequence contributions bias glycation outcomes

The methylglyoxal-derived hydroimidazolone isomer, MGH-1, is an abundant advanced glycation end-product (AGE) associated with disease and age-related disorders. As AGE formation occurs spontaneously and without an enzyme, it remains unknown why certain sites on distinct proteins become modified with...

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Detalles Bibliográficos
Autores principales: McEwen, Joseph M., Fraser, Sasha, Guir, Alexxandra L. Sosa, Dave, Jaydev, Scheck, Rebecca A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175500/
https://www.ncbi.nlm.nih.gov/pubmed/34083524
http://dx.doi.org/10.1038/s41467-021-23625-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175500/
https://www.ncbi.nlm.nih.gov/pubmed/34083524
http://dx.doi.org/10.1038/s41467-021-23625-8

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