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Perilipin 5 links mitochondrial uncoupled respiration in brown fat to healthy white fat remodeling and systemic glucose tolerance

Exposure of mice or humans to cold promotes significant changes in brown adipose tissue (BAT) with respect to histology, lipid content, gene expression, and mitochondrial mass and function. Herein we report that the lipid droplet coat protein Perilipin 5 (PLIN5) increases markedly in BAT during expo...

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Detalles Bibliográficos
Autores principales: Gallardo-Montejano, Violeta I., Yang, Chaofeng, Hahner, Lisa, McAfee, John L., Johnson, Joshua A., Holland, William L., Fernandez-Valdivia, Rodrigo, Bickel, Perry E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175597/
https://www.ncbi.nlm.nih.gov/pubmed/34083525
http://dx.doi.org/10.1038/s41467-021-23601-2