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Perilipin 5 links mitochondrial uncoupled respiration in brown fat to healthy white fat remodeling and systemic glucose tolerance
Exposure of mice or humans to cold promotes significant changes in brown adipose tissue (BAT) with respect to histology, lipid content, gene expression, and mitochondrial mass and function. Herein we report that the lipid droplet coat protein Perilipin 5 (PLIN5) increases markedly in BAT during expo...
Autores principales: | Gallardo-Montejano, Violeta I., Yang, Chaofeng, Hahner, Lisa, McAfee, John L., Johnson, Joshua A., Holland, William L., Fernandez-Valdivia, Rodrigo, Bickel, Perry E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175597/ https://www.ncbi.nlm.nih.gov/pubmed/34083525 http://dx.doi.org/10.1038/s41467-021-23601-2 |
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