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Marked Mild Cognitive Deficits in Humanized Mouse Model of Alzheimer’s-Type Tau Pathology

Hyperphosphorylation and the subsequent aggregation of tau protein into neurofibrillary tangles (NFTs) are well-established neuropathological hallmarks of Alzheimer’s disease (AD) and associated tauopathies. To further examine the impact and progression of human tau pathology in neurodegenerative co...

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Detalles Bibliográficos
Autores principales: Cho, Joshua D., Kim, Yoon A., Rafikian, Elizabeth E., Yang, Mu, Santa-Maria, Ismael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175658/
https://www.ncbi.nlm.nih.gov/pubmed/34093145
http://dx.doi.org/10.3389/fnbeh.2021.634157