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Marked Mild Cognitive Deficits in Humanized Mouse Model of Alzheimer’s-Type Tau Pathology
Hyperphosphorylation and the subsequent aggregation of tau protein into neurofibrillary tangles (NFTs) are well-established neuropathological hallmarks of Alzheimer’s disease (AD) and associated tauopathies. To further examine the impact and progression of human tau pathology in neurodegenerative co...
Autores principales: | Cho, Joshua D., Kim, Yoon A., Rafikian, Elizabeth E., Yang, Mu, Santa-Maria, Ismael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175658/ https://www.ncbi.nlm.nih.gov/pubmed/34093145 http://dx.doi.org/10.3389/fnbeh.2021.634157 |
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