Alpha-synuclein increases in rodent and human spinal cord injury and promotes inflammation and tissue loss

Synucleinopathies are neurodegenerative diseases in which α-synuclein protein accumulates in neurons and glia. In these diseases, α-synuclein forms dense intracellular aggregates that are disease hallmarks and actively contribute to tissue pathology. Interestingly, many pathological mechanisms, incl...

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Detalles Bibliográficos
Autores principales: Sauerbeck, Andrew D., Goldstein, Evan Z., Alfredo, Anthony N., Norenberg, Michael, Marcillo, Alexander, McTigue, Dana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175699/
https://www.ncbi.nlm.nih.gov/pubmed/34083630
http://dx.doi.org/10.1038/s41598-021-91116-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175699/
https://www.ncbi.nlm.nih.gov/pubmed/34083630
http://dx.doi.org/10.1038/s41598-021-91116-3

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