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Alpha-synuclein increases in rodent and human spinal cord injury and promotes inflammation and tissue loss
Synucleinopathies are neurodegenerative diseases in which α-synuclein protein accumulates in neurons and glia. In these diseases, α-synuclein forms dense intracellular aggregates that are disease hallmarks and actively contribute to tissue pathology. Interestingly, many pathological mechanisms, incl...
Autores principales: | Sauerbeck, Andrew D., Goldstein, Evan Z., Alfredo, Anthony N., Norenberg, Michael, Marcillo, Alexander, McTigue, Dana M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175699/ https://www.ncbi.nlm.nih.gov/pubmed/34083630 http://dx.doi.org/10.1038/s41598-021-91116-3 |
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