Phenotypic analysis of catastrophic childhood epilepsy genes

Genetic engineering techniques have contributed to the now widespread use of zebrafish to investigate gene function, but zebrafish-based human disease studies, and particularly for neurological disorders, are limited. Here we used CRISPR-Cas9 to generate 40 single-gene mutant zebrafish lines represe...

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Detalles Bibliográficos
Autores principales: Griffin, Aliesha, Carpenter, Colleen, Liu, Jing, Paterno, Rosalia, Grone, Brian, Hamling, Kyla, Moog, Maia, Dinday, Matthew T., Figueroa, Francisco, Anvar, Mana, Ononuju, Chinwendu, Qu, Tony, Baraban, Scott C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175701/
https://www.ncbi.nlm.nih.gov/pubmed/34083748
http://dx.doi.org/10.1038/s42003-021-02221-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175701/
https://www.ncbi.nlm.nih.gov/pubmed/34083748
http://dx.doi.org/10.1038/s42003-021-02221-y

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