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Phenotypic analysis of catastrophic childhood epilepsy genes
Genetic engineering techniques have contributed to the now widespread use of zebrafish to investigate gene function, but zebrafish-based human disease studies, and particularly for neurological disorders, are limited. Here we used CRISPR-Cas9 to generate 40 single-gene mutant zebrafish lines represe...
Autores principales: | Griffin, Aliesha, Carpenter, Colleen, Liu, Jing, Paterno, Rosalia, Grone, Brian, Hamling, Kyla, Moog, Maia, Dinday, Matthew T., Figueroa, Francisco, Anvar, Mana, Ononuju, Chinwendu, Qu, Tony, Baraban, Scott C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175701/ https://www.ncbi.nlm.nih.gov/pubmed/34083748 http://dx.doi.org/10.1038/s42003-021-02221-y |
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