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A functional motif of long noncoding RNA Nron against osteoporosis

Long noncoding RNAs are widely implicated in diverse disease processes. Nonetheless, their regulatory roles in bone resorption are undefined. Here, we identify lncRNA Nron as a critical suppressor of bone resorption. We demonstrate that osteoclastic Nron knockout mice exhibit an osteopenia phenotype...

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Detalles Bibliográficos
Autores principales: Jin, Fujun, Li, Junhui, Zhang, Yong-Biao, Liu, Xiangning, Cai, Mingxiang, Liu, Meijing, Li, Mengyao, Ma, Cui, Yue, Rui, Zhu, Yexuan, Lai, Renfa, Wang, Zuolin, Ji, Xunming, Wei, Huawei, Dong, Jun, Liu, Zhiduo, Wang, Yifei, Sun, Yao, Wang, Xiaogang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175706/
https://www.ncbi.nlm.nih.gov/pubmed/34083547
http://dx.doi.org/10.1038/s41467-021-23642-7