Pre-emptive pharmacological inhibition of fatty acid–binding protein 4 attenuates kidney fibrosis by reprogramming tubular lipid metabolism

Kidney fibrosis is a hallmark of chronic kidney disease (CKD) progression that is caused by tubular injury and dysregulated lipid metabolism. Genetic abolition fatty acid-binding protein 4 (FABP4), a key lipid transporter, has been reported to suppress kidney interstitial fibrosis. However, the role...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Yuting, Dai, Yue, Song, Kaixin, Huang, Yi, Zhang, Le, Zhang, Cuntai, Yan, Qi, Gao, Hongyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175732/
https://www.ncbi.nlm.nih.gov/pubmed/34083513
http://dx.doi.org/10.1038/s41419-021-03850-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8175732/
https://www.ncbi.nlm.nih.gov/pubmed/34083513
http://dx.doi.org/10.1038/s41419-021-03850-1

Ejemplares similares